ALBA Fluorescence Correlation Spectrometer
ALBA Fluorescence Correlation Spectrometer
ALBA is a dual channel spectrometer for fluorescence correlation (or, fluctuation) measurements optimized for either single-photon or multi-photon excitation through an epifluorescence microscope¡¡

1. Molecular Dynamics
2. Kinetic rate constants
3. Antibody-antigen interactions
4. Ligand-receptor interactions
5. Nucleic acid hybridization
6. Molecular aggregation, polydispersity, and molecular weight

Fluorescence Correlation Spectrometer
ALBA, spectroscopy on single molecules

ACQUISITION MODES ALBA acquires either in time-mode (the classical way: photons acquired in time intervals are counted) or in photon mode (time delay between one photon and the next one is measured and an histogram is built). A 2-channel data acquisition card receives the data stream from the detectors and passes them on to the computer. Raw data are stored in a data file for further processing. No need anymore to reject an autocorrelation function because of large particles interference. Raw data can be purged from large particles presence and the autocorrelation function can be recalculated.
EXCITATION MODALITY Single photon excitation (using an argon ion, kripton ion, or dye- laser); or multi- photon excitation (using a Ti:Sapphire laser).
MICROSCOPES ALBA can be interfaced to either an Olympus or a Nikon epifluorescence microscope.
DETECTORS Light detectors are cooled photomultiplier tubes or avalanche photodiodes. The system is provided for single channel or dual channel data acquisition for cross-correlation measurements.
THE UNIQUE INSTRUMENT ALBA can be upgraded for steady-state and lifetime measurements. All in a single instrument!